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    Hugues Duffau, MD, PhD

    Professor and Chairman
    Montpellier University Medical Center

    Hugues DUFFAU (MD, PhD) is Professor and Chairman of the Neurosurgery Department in the Montpellier University Medical Center and Head of the INSERM 1191 Team "Plasticity of the central nervous system, human stem cells and glial tumors" at the Institute of Functional Genomics of Montpellier (University of Montpellier, France). He is an expert in the awake cognitive neurosurgery of slow-growing brain tumors, as low-grade gliomas, a routine which he has developed since more than 25 years. His fundamental approach is centered on the concepts of the brain connectomics and neuroplasticity, breaking with the traditional localizationist view of cerebral processing. For his innovative work in neurosurgery and neurosciences, he was awarded Doctor Honoris Causa seven times, and he was the youngest recipient of the prestigious Herbert Olivecrona Award (Nobel Prize of neurosurgery) from the Karolinska Institute in Stockholm. He has written five textbooks and over 530 publications in international journals ranging from neurosurgery and neurooncology to fundamental neurosciences, including cognitive sciences and brain plasticity, for a total of more than 50,000 citations and with an h-index of 123. He gave more than 750 invited lectures, and was invited as a visiting professor in more than 70 institutions. He is member of Editorial boards of many journals (as Brain and Language, Neurosurgery or Neuro-oncology) and ad-hoc reviewer for around 100 journals (over 950 reviews) including: NEJM, Lancet Oncology, Nature Medicine, Nature Reviews Neuroscience, Nature Reviews Neurology; Annals of Neurology, Brain, Cerebral Cortex, Trends in Cognitive Science, Current Biology, etc. He is member of many societies, such as the French Academy of Medicine, the French Academy of Surgery, the Royal Academy of Medicine of Belgium, the World Academy of Neurological Surgery, etc…

    Main publications:
    . Duffau H. Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity. Lancet Neurology. 2005;4:476-86
    . Duffau H. Stimulation mapping of white matter tracts to study brain functional connectivity. Nature Rev Neurol. 2015;11:255-65
    . Herbet G, Maheu M, Costi E, Lafargue G, Duffau H. Mapping neuroplastic potential in brain-damaged patients. Brain. 2016;139:829-44
    . Herbet G, Duffau H. Revisiting the functional anatomy of the human brain: Toward a meta-networking theory of cerebral functions. Physiological Reviews. 100:1181-1228, 2020
    . Herbet G, Duffau H. Contribution of the medial eye field network to the voluntary deployment of visuospatial attention. Nature Communications. 2022;13(1):328
    . Lemaitre AL, Herbet G, Ng S, Moritz-Gasser S, Duffau H. Cognitive preservation following awake mapping-based neurosurgery for low-grade gliomas: A longitudinal, within-patient design study. Neuro-Oncology. 24:781-793, 2022
    . Ng S, Valdes PA, Moritz-Gasser S, Lemaitre AL, Duffau H, Herbet G. Intraoperative functional remapping unveils evolving patterns of cortical plasticity. Brain. 2023;146:3088-3100.
    . Ng S, Rigau V, Moritz-Gasser S, Goze C, Darlix A, Herbet G, Duffau H. Long-term autonomy, professional activities, cognition, and overall survival after awake functional-based surgery in patients with IDH-mutant grade 2 gliomas: a retrospective cohort study. Lancet Regional Health – Europe 46: 101078, 2024


    Disclosure(s): No financial relationships to disclose

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