Single-stage Posterior Circumferential Stabilization with Mesh Cages for Thoracic and Lumbar Spine Fractures: A Meta-analysis

Introduction: Thoracic and lumbar spine fractures present complex challenges, often necessitating stabilization to prevent further neurological damage. Single-stage posterior circumferential stabilization with mesh cages offers a potentially less invasive alternative, combining anterior and posterior support for spine reconstruction. This meta-analysis examines the effectiveness and safety of this approach for patients with thoracic and lumbar spine fractures.

Methods: Relevant studies from 2010 to 2023 were sourced from PubMed, Embase, and Cochrane Library. Using Python and R, data from selected studies were analyzed to assess outcomes like kyphotic angle correction, segmental height restoration, pain reduction (VAS score), and fusion rates. Random-effects models provided pooled estimates, while heterogeneity was evaluated with the I² statistic.

Results: From 12 studies comprising 1,254 patients, the single-stage procedure achieved an average kyphotic angle correction of 13.9° (95% CI: 12.2–15.6, p < 0.001) and segmental height restoration of 7.1 mm (95% CI: 5.4–8.8, p < 0.001). Fusion was reported in 87% of cases within 12 months. Postoperative VAS scores showed significant pain reduction (mean decrease: 5.6 points). Heterogeneity was moderate (I² = 52%), attributed to varied fracture severity. Complications included minimal recurrence of kyphotic deformity in 8% of patients and segmental height loss in 6%.

Conclusion : Single-stage posterior stabilization with mesh cages provides substantial kyphotic correction, height restoration, and pain reduction, with high fusion rates and minimal complications, validating it as a safe, effective option for thoracic and lumbar spine fractures. Further randomized studies are recommended to strengthen these findings.